Join us for our webinar “Neurons are talking…are you listening?” with Prof. Dr. Kasri from Radboud UMC
— Bridging the gap between molecular and functional aspects of neurodevelopment —
Wednesday, September 4 | 5–6 pm CEST
Advancements in human genetics have enabled the identification of numerous genes linked to neurodevelopmental disorders (NDDs), including epilepsy and autism spectrum disorders (ASD). Despite progress in understanding the genetic underpinnings of NDDs, a significant disparity remains between genetic discoveries and understanding the underlying pathophysiology.
Are you a neurobiology researcher looking to stay ahead in the science of neurodevelopmental disorders (NDDs) like epilepsy and autism?
Are you curious to learn how optimized MEA technology helps to gain authentic insights into neuronal activity?
We invite you to an exclusive webinar led by Prof. Dr. Nael Nadif Kasri, from Radboud UMC, Netherlands, a leading expert in the field, and co-hosted with MaxWell Biosystems.
Prof. Dr. Nael Nadif Kasri, from Radboud UMC, Netherlands, will present his pioneering work in analyzing patient-derived neural lineages using microelectrode arrays (MEA) coated with Biolaminin®. A Q&A session will follow Prof. Dr. Kasri’s presentation.
Webinar highlights:
- Neuronal activity and NDDs: Dr. Kasri’s team analyzed over 1,000 recordings from 43 NDD-related cell lines, identifying specific activity phenotypes and gene modules linked to different disorders.
- Optimized MEA combined with RNA-sequencing: Learn how combining RNA-sequencing with biorelevant MEA recordings can uncover co-regulated gene modules that influence neuronal activity, providing new insights into the molecular basis of NDDs.
- Bridging genetics and function: Discover how this research platform offers a novel approach to bridging the gap between genetic mutations and their functional consequences in neurons, with implications for developing targeted treatment.
Can’t make it? Register anyway and we will send you the recording with key points!
About Prof. Dr. Nael Nadif Kasri
Prof. Dr. Nael Nadif Kasri completed his PhD in molecular biology at KU Leuven. After his PhD, he worked as a postdoctoral researcher in neurobiology at Cold Spring Harbor Laboratory (CSHL), New York. In 2010, he started his independent research group at Radboud UMC, where he is part of the Donders Institute. His research focuses on understanding the synaptic basis of neurodevelopmental disorders. In particular, his expertise in generating patient-derived neural lineages and their neurophysiological analysis at the single-cell and network levels (MEA) is pioneering this novel research field.
About BioLamina and Biolaminin® technology
BioLamina is a biotechnology company with a scientific base and heritage in matrix biology and cell culture research. It supports scientists who have struggled for decades to grow pluripotent stem cells and other primary cells in the lab. By providing tools for efficient and easy cell culture, BioLamina aims to ease the path toward safe and effective cell therapies and make better cell assays and models for increasing accuracy in drug discovery and development. The power of Biolaminin® substrates, developed by BioLamina, has been demonstrated in numerous publications, and they will continue to provide vital support to the stem cell community—from scientific concepts to clinical studies. Based in Stockholm (Sweden), the company currently employs 90 people.
About MaxWell Biosystems
MaxWell Biosystems is a well-established technology leader dedicated to boosting scientific breakthroughs and accelerating drug discovery. Our cutting-edge, easy-to-use platforms with high-density microelectrode arrays empower researchers in neuroscience, stem cell engineering, neuroengineering, and other applications to gain unparalleled insights into neurological diseases, therapeutic development, and beyond. By providing advanced technology to scientists globally in academia and pharma, we aim to transform scientific research and contribute to significant advancements in health and medicine.