BioLamina products

We offer an expansive portfolio of human recombinant laminin cell culture substrates for a variety of applications in 2D and 3D. Our portfolio of Biolaminin® isoforms provides reliable expansion of pluripotent cells and successful differentiation and maintenance of specialized cell types. The authentic cell culture environment allows more consistent and reliable cellular responses and improves cell functionality. 


Cell culture matrices

Almost all cells in the human body grow on specific laminins. With our human recombinant laminin substrates, pluripotent stem cells, adult stem cells and tissue-specific cells can now be cultured in a physiologically relevant environment, even in 3D culture.


  • Biolaminin 521 CTG (CT521)

    Human recombinant laminin 521

    Biolaminin 521 CTG is a full-length, human, recombinant laminin 521 substrate, the only one of its kind on the market, providing an optimal environment for feeder-free culture of human PSCs, MSCs and most anchorage-dependent progenitor cell types. CT521 is animal origin-free to the secondary level and designed for clinical studies.
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  • Biolaminin 521 MX (MX521)

    Human recombinant laminin 521

    Biolaminin 521 MX is the natural laminin for pluripotent stem cells and therefore reliably facilitates self-renewal of human ES and iPS cells in a chemically defined, feeder-free stem cell culture system. MX521 is animal origin-free to the secondary level.
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  • Biolaminin 521 LN (LN521)

    Human recombinant laminin 521

    Biolaminin 521 LN is the natural laminin for pluripotent stem cells and therefore reliably facilitates self-renewal of human ES and iPS cells in a chemically defined, feeder-free and animal origin-free stem cell culture system. LN521 is animal origin-free to the primary level.
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  • Biosilk 521

    3D culture substrate

    Biosilk 521 is a natural biomaterial made of spider silk and laminin 521 – an ideal 3D culture substrate for integration, expansion, and long-term differentiation of human pluripotent stem cells and different progenitor cells.
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  • Biosilk

    3D culture substrate

    Biosilk is a natural biomaterial made from recombinant spider silk protein, a useful tool for a wide range of 3D culture applications, such as organoid culture and other tissue engineering applications. Biosilk can be mixed with any Biolaminin matrix.
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  • LAMscreen

    Laminin isoform kit

    Order a set of four different Biolaminin LN products to find the optimal cell culture environment for your specific system.
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  • Biolaminin 111 LN (LN111)

    Human recombinant laminin 111

    Biolaminin 111 is commonly used as a general attachment protein for many cell types in vitro.
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  • Biolaminin 121 LN (LN121)

    Human recombinant laminin 121

    Biolaminin 121 can be used as a general attachment protein for most cell types in vitro – in particular for hepatic and neural differentiation and to enhance neurite outgrowth.
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  • Biolaminin 211 LN (LN211)

    Human recombinant laminin 211

    Biolaminin 211 supports the growth, survival, and differentiation of a wide range of tissue-specific cell types, including motor neurons, cardiac cells, and skeletal muscle cells.
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  • Biolaminin 221 LN (LN221)

    Human recombinant laminin 221

    Biolaminin 221 supports the growth, survival, and differentiation of a wide range of tissue-specific cell types, including cardiac cells and skeletal muscle cells.
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  • Biolaminin 332 LN (LN332)

    Human recombinant laminin 332

    Biolaminin 332 supports cells in epithelial basement membranes, lining surfaces of the body such as the skin, hair follicles, oral cavity, gastrointestinal and urinary tract, lungs, and different glands.
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  • Biolaminin 411 LN (LN411)

    Human recombinant laminin 411

    Biolaminin 411 supports many diverse tissue cell types such as cells from the pancreas and the vascular, immune, nervous, hematopoietic systems.
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  • Biolaminin 421 LN (LN421)

    Human recombinant laminin 421

    Biolaminin 421 supports several tissue-specific cell types such as endothelial cells and kidney cells, and has been suggested to be important for renal, synaptic and inflammatory functions.
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  • Biolaminin 511 LN (LN511)

    Human recombinant laminin 511

    Biolaminin 511 is the natural laminin for mouse embryonic stem cells and allows sustained pluripotency without the need to use feeder cells or differentiation inhibitors like LIF.
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3D cell culture

Our Biosilk product provides a defined 3D culture network that promotes long-term cell survival without cell encapsulation. The biorelevant Biolaminin substrates can be used together with Biosilk or other 3D cell culture systems for improved cell function.


  • Biosilk 521

    3D culture substrate

    Biosilk 521 is a natural biomaterial made of spider silk and laminin 521 – an ideal 3D culture substrate for integration, expansion, and long-term differentiation of human pluripotent stem cells and different progenitor cells.
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  • Biosilk

    3D culture substrate

    Biosilk is a natural biomaterial made from recombinant spider silk protein, a useful tool for a wide range of 3D culture applications, such as organoid culture and other tissue engineering applications. Biosilk can be mixed with any Biolaminin matrix.
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Cell therapy grade products

Cell therapy grade (CTG) products are designed for clinical research with documented quality. With the CTG products, scientists are supported throughout their cell therapy development process.


  • Biolaminin 521 CTG (CT521)

    Human recombinant laminin 521

    Biolaminin 521 CTG is a full-length, human, recombinant laminin 521 substrate, the only one of its kind on the market, providing an optimal environment for feeder-free culture of human PSCs, MSCs and most anchorage-dependent progenitor cell types. CT521 is animal origin-free to the secondary level and designed for clinical studies.
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  • Neural cells

    Biorelevant culture of neural cells on Biolaminin substrates Laminins are widely expressed in the nervous system and are essential for […]
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  • Eye cells

    Biorelevant culture of eye cells Laminin proteins are important components in the eye microenvironment Biolaminin products have been succesfully used […]
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  • Pluripotent stem cells

    Biorelevant culture of human ES and iPS cells on Biolaminin substrates Biolaminin 521 successfully replicates the genuine human stem cell niche […]
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  • 3D culture

    3D cell culture using Biolaminin and Biosilk matrices 3D culture systems for disease modeling, drug screening and regenerative medicine Cell […]
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  • Large-scale stem cell production and clinical use

    Biolaminin substrates in large-scale manufacturing and clinical use Scaling up high-quality cell production for clinical needs A scalable system for […]
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