A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization

Etoc F., Metzger J., Ruzo A., Kirst C., Yoney A., Ozair Z.M, Brivanlou A.H., Siggia E.D

Developmental cell, 2016

Here the authors used colonies of hESC grown on the micropatterned substrate and differentiated with BMP4 to model patterning events in the human embryo. Coated Costar Transwells with LN521.