The hippocampal laminin matrix is dynamic and critical for neuronal survival

Zu-Lin Chen, Justin A. Indyk, and Sidney Strickland

Molecular Biology of the Cell, 2003


In this article, the authors investigated how laminin is involved in neuronal viability by infusing laminin-1 (α1,β1,γ1) into the mouse hippocampus. The results demonstrate that the laminin matrix is a dynamic structure amenable to modification by exogenous molecules.