FK506 positively regulates the migratory potential of melanocyte-derived cells by enhancing syndecan-2 expression

Hyejung Jung and Eok-Soo Oh

Pigment Cell Melanoma Res, 2016

The authors report that topical tacrolimus (FK506) treatment, known to promote repigmentation, enhanced cell spreading on laminin-332 and increased migration in both melanocytes and melanoma cells by enhancing syndecan-2 expression.