Molecular interactions in the retinal basement membrane system: a proteomic approach

Manimalha Balasubramani, Emanuel M Schreiber, Joseph Candiello, G K Balasubramani, Justin Kurtz, Willi Halfter.

Matrix Biol, 2010


The authors describe a direct analysis of an in vivo basement membrane (BM) system using a mass spectrometry (MS) based proteomics approach. Nidogens-1 and -2, laminin subunits α1, α5, β2, and γ1, agrin, collagen XVIII, perlecan, FRAS1 and FREM2 were the most abundant BM protein components.