Properly formed but improperly localized synaptic specializations in the absence of laminin α4

Bruce L. Patton, Jeanette M. Cunningham, Jill Thyboll, Jarkko Kortesmaa, Håkan Westerblad, Lars Edström, Karl Tryggvason & Joshua R. Sanes.

Nature Neuroscience, 2001


The authors show that the formation and localization of synaptic specializations are regulated separately, and α4β2γ1 (laminin-421) is critical in the latter process.