Organotypic arrangement of mouse embryonic lung cells on a basement membrane extract: involvement of laminin
L Schuger, KS O’Shea, BB Nelson, J Varani.
In this article, the authors cultured single cell suspensions generated by trypsinization of lungs removed from day 12 embryos. The results strongly supports a role for the basement membrane in the organotypic rearrangement of embryonic lung cells and subsequent in vitro cyst formation and budding of the reestablished epithelium.
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