Application note

Revolutionizing β-cell culture

Discover how Biolaminin® 521, 511, and 411 substrates enhance differentiation, maturation, and functionality of stem cell–derived and primary islets — improving cell polarity, insulin secretion, and in vitro survival while supporting clinically compliant workflows.

What’s inside

• Overview of full-length pancreatic laminins
• Efficient generation of functional stem cell–derived islets using Biolaminin 521 and 511
• How Biolaminin 521, 511, and 411 support in vitro survival and expansion of primary pancreatic islets
• How full-length laminins enhance islet function and and β-cell organization