Application note

Large-scale cell production

Biolaminin® full-length laminins support standardized, high-yield expansion of pluripotent stem cells in scalable systems — improving consistency, maintaining pluripotency, and facilitating clinically relevant cell manufacturing in both open and closed bioprocessing platforms.

What’s inside

  • Key benefits of Biolaminin for scale-up: biologically relevant support, high expansion rates, minimized variation, and defined animal-origin–free matrices
  • Microcarrier-based hPSC expansion in stirred/agitated systems with maintained viability and pluripotency
  • Closed hollow-fiber expansion systems demonstrating improved proliferation and preserved differentiation potential
  • Applications in scalable production of megakaryocytes (platelets) and red blood cells from pluripotent stem cells
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