
Application note
Modelling the kidney
in 2D and 3D
Discover how Biolaminin® 521 and 511 substrates enhance 2D and 3D kidney models — improving barrier integrity, cell maturation, and functionality in organoid and organ-on-chip systems while supporting reproducible, animal origin-free workflows.
What’s inside
- Overview of full-length laminins in kidney basement membranes
- Generation of functional 2D and 3D kidney models using Biolaminin 521 & 511
- Enhanced barrier integrity and maturation of glomerular and tubular cells
- Application in organoid and organ-on-chip technologies for disease modelling