Archive Results

  • Application note 023-01: Next generation xeno-free and defined skin cell culture – on Biolaminin® 521 (LN521) and Biolaminin 511 (LN511) substrates)

    Skin is the largest organ of the body and our first line of defense against pathogens and environmental impacts. The skin is composed of two main layers, epidermis and dermis. They are separated by an ultrathin basement membrane (BM), highly enriched in laminin proteins, particularly the isoforms 332, 331, 521 and 511. Laminin 332/331 are mostly associated with adhesion and maturation and 521/511 with adhesion and proliferation. The complex interaction of BM and cells is essential for healthy skin development and tissue homeostasis, and essential part of the stem cell niche of the skin.
  • Application note 017: Xeno-free and defined keratinocyte culture on Biolaminin® 521 and Biolaminin 511 substrates

  • Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate

    Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate E. Chermnykh, E. and Kalabusheva, and E. Vorotelyak Int J […]
  • Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons

    Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons Li-Yang Chiang, Kate Poole, Beatriz E Oliveira, Neuza Duarte, Yinth […]
  • Human amnion contains a novel laminin variant, laminin 7, which like laminin 6, covalently associates with laminin 5 to promote stable epithelial-stromal attachment

    Human amnion contains a novel laminin variant, laminin 7, which like laminin 6, covalently associates with laminin 5 to promote […]
  • Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis

    Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis Jing Gao, Mindy C. DeRouen, […]
  • Laminin-10 is crucial for hair morphogenesis

    Laminin-10 is crucial for hair morphogenesis Jie Li, Julia Tzu, Yi Chen, Yan-Ping Zhang, Ngon T Nguyen, Jing Gao, Maria […]