Here is a selection of publications where different laminin isoforms were used to create more authentic cell culture systems.

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  • Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis

    Jing Gao, Mindy C. DeRouen, Chih-Hsin Chen, Michael Nguyen, Ngon T. Nguyen, Hiroyuki Ido, Kenji Harada, Kiyotoshi Sekiguchi, Bruce A. Morgan, Jeffery H. Miner, Anthony E. Oro, and M. Peter Marinkovich. Genes Dev, 2008

    Abnormal adhesion of grafted corneal endothelial cells (CECs) affects the application of intracameral injection for corneal endothelial dysfunction therapy. The authors explored whether laminin 511 (LN511) improves the therapeutic function of the intracameral CEC injection. Injected LN511 was found to be able to settle and form a coating on the posterior surface of Descemet's membrane (DM). The data suggests that the strategy of LN511 precoating and CECs' intracameral injection could be a potential method for the therapy of corneal endothelial dysfunction.

  • Laminin-10 is crucial for hair morphogenesis

    Jie Li, Julia Tzu, Yi Chen, Yan-Ping Zhang, Ngon T Nguyen, Jing Gao, Maria Bradley, Douglas R Keene, Anthony E Oro, Jeffrey H Miner, M Peter Marinkovich. EMBO J, 2003

    This article describes the essential role of laminin-10 (laminin-511) in hair follicle development.