Scale automated cell culture with Biolaminin ®
Biolaminin® substrates provide a consistent, chemically defined, and automation-friendly cell culture matrix. These features enable the efficient, large-scale production of billions of high-quality cells required for cell therapy.
Biolaminin enables billions of cells for therapy
Automation is essential for achieving scalable and reproducible cell culture processes across research, biomanufacturing, and regenerative medicine. However, a persistent challenge in automating cell therapy manufacturing is ensuring that cells maintain their biological consistency and functionality. Biolaminin® enables researchers to efficiently produce the billions of high-quality cells required for cell therapy by providing a consistent, chemically defined, and automation-friendly cell culture matrix.
How Biolaminin powers automated cell culture
Human recombinant laminin proteins closely mimic the natural cell environment, supporting robust cell attachment, proliferation, and phenotype maintenance during long-term expansion.
Compatibility with automated cell culture equipment platforms
Cell X technologies
Cell X Technologies automated cell culturing platform specializing in iPSC derivation, automated picking, stem cell maintenance, and differentiation.
Corning Ascent
Corning’s Ascent fixed bed bioreactor (FBR) for PSC scale-up (x10^9).
Terumo Quantum Flex
Terumo’s Quantum Flex hollow-fiber bioreactor for PSC scale-up (x10^7).
CellenOne
Cellenion’s cellenONE single-cell dispenser for automated cell line development.
Application note
Improving automated cell culture with full length Biolaminin 521
See data from peer-reviewed publications showing how Biolaminin® substrates improve cell outcomes in various automated culture systems.
Extend your research
Curated content to support your next steps in clinical translation
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Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System
The authors describe the use Quantum Cell Expansion System (QES) as an iPSC […]
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Methods for Automated Single Cell Isolation and Sub-Cloning of Human Pluripotent Stem Cells
This publication describes automated workflows to facilitate high-throughput hPSC clo […]
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Expansion of induced pluripotent stem cells under consideration of bioengineering aspects: part 2
The manufacturing of allogeneic cell therapeutics based on human-induced pluripotent […]
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Recommended products
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Biolaminin 521 MX (MX521)
Full-length human recombinant laminin-521
Biolaminin 521 MX is a full-length laminin-521 substrate designed for research aiming for clinical applications. -
Biolaminin 521 LN (LN521)
Full-length human recombinant laminin-521
Biolaminin 521 LN is a full-length laminin-521 substrate—the natural laminin for pluripotent stem cells, reliably facilitating ESC and iPSC self-r […]
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