Biolaminin 521 MX (MX521)

Full-length human recombinant laminin-521

Product NumberUnit PriceAmountSize
MX521-0501 500 μg1 x 5 ml

Biolaminin 521 MX is a full-length laminin-521 substrate designed for research aiming for clinical applications. Laminin-521 is the natural laminin for pluripotent stem cells, reliably facilitating ESC and iPSC self-renewal in a chemically defined, xeno-free stem cell culture system. It also uniquely promotes the identity and growth of many tissue-specific human cell types. MX521 is animal origin-free to the secondary level.

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Biolaminin: The only full-length laminin proteins on the market

Biolaminin 521 MX (MX521-0501) comprises full-length, human recombinant laminin-521 protein, a cell culture matrix designed for robust cultivation of human pluripotent stem cells (hPSCs) in studies aiming for clinical applications. As an inherent stem cell niche protein, full-length laminin-521 provides a biologically relevant environment leading to improved survival and efficient growth from single-cell cultures to large-scale production.

Learn more about full-length laminins:

The matrix to trust for your stem cell therapy success

Successful pluripotent stem cell therapy requires reproducibility, global regulatory compliance, and most importantly, the generation of truly functional clinical cells. Biolaminin®, the only full-length laminin substrate, excels in supporting all these aspects.

Controlled differentiation with tissue-specific laminin

Beyond its fundamental role in sustaining stem cell cultures, laminin-521 also augments cell differentiation, fostering the maturation, polarization, and organization of specialized cell types. It also stands as the preferred option for culturing a set of primary cell types given its natural occurrence in tissues such as the nervous system, pancreas, and eye.

Supporting your clinical cell production process from research to commercialized therapy

The Biolaminin MX and CT laminin-521 products are designed for clinical translation with comprehensive quality documentation.


  • Pluripotent stem cells

    Biorelevant culture of human ES and iPS cells on Biolaminin substrates Biolaminin 521 successfully replicates the genuine human stem cell niche […]
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  • 3D culture

    Biosilk and Biolaminin key advantages 3D cell culture and organoid formation 3D culture systems for disease modeling, drug screening, and […]
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  • Clonal stem cell culture

    Biorelevant clonal stem cell culture on Biolaminin substrates Biolaminin 521 successfully replicates the genuine human stem cell niche in vitro […]
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  • iPSC reprogramming and expansion

    Reprogramming and expansion of human iPS cells on Biolaminin substrates High-efficiency iPSC reprogramming and expansion on Biolaminin 521 Human recombinant Biolaminin […]
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  • Neural cells

    Biorelevant culture of neural cells on Biolaminin substrates Laminins are widely expressed in the nervous system and are essential for […]
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  • Hepatocytes and hepatoblasts

    Biorelevant culture of liver cells on Biolaminin substrates Several laminins play a vital role in liver progenitor cell-mediated regeneration The […]
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  • Eye cells

    Biorelevant culture of eye cells on full-length laminin-521 Laminin proteins are integral components in the eye microenvironment Biolaminin products have […]
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  • Endothelial cells

    Biorelevant culture of endothelial cells Biolaminin isoforms for vascular endothelial cell culture Endothelial cells that make up the vascular network […]
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