Archive Results

  • Integration of xeno-free single-cell cloning in CRISPR-mediated DNA editing of human iPSCs improves homogeneity and methodological efficiency of cellular disease modeling

    Integration of xeno-free single-cell cloning in CRISPR-mediated DNA editing of human iPSCs improves homogeneity and methodological efficiency of cellular disease modeling Atefeh […]
  • Application note 023-01: Next generation xeno-free and defined skin cell culture – on Biolaminin® 521 (LN521) and Biolaminin 511 (LN511) substrates)

    Skin is the largest organ of the body and our first line of defense against pathogens and environmental impacts. The skin is composed of two main layers, epidermis and dermis. They are separated by an ultrathin basement membrane (BM), highly enriched in laminin proteins, particularly the isoforms 332, 331, 521 and 511. Laminin 332/331 are mostly associated with adhesion and maturation and 521/511 with adhesion and proliferation. The complex interaction of BM and cells is essential for healthy skin development and tissue homeostasis, and essential part of the stem cell niche of the skin.
  • Instructions 012: Biosilk® and Biolaminin® free-floating scaffolds in 96-well plate for hPSC culture

    Guideline for human Pluripotent Stem Sell integration into free-floating Biosilk scaffolds fitted into 96-well plates.
  • Application note 018-02: BioLamina products in research and manufacturing – Biolaminin® matrices for all steps and scales

    Clinically adaptable Biolaminin cell adhesion coating for higher yield in bioreactor systems
  • Application note 017: Xeno-free and defined keratinocyte culture on Biolaminin® 521 and Biolaminin 511 substrates

  • A Biomimetic Electrospun Membrane Supports the Differentiation and Maturation of Kidney Epithelium from Human Stem Cells

    A Biomimetic Electrospun Membrane Supports the Differentiation and Maturation of Kidney Epithelium from Human Stem Cells Mou, X., Shah, J., […]
  • Application note 018: Large-scale cell production

    Clinically adaptable Biolaminin cell adhesion coating for higher yield in bioreactor systems
  • Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System

    Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System […]
  • Application note 001: Weekend free hPSC culture using Biolaminin 521

    No need to feed your stem cells during weekends with the help of the biorelevant matrix
  • Instructions 011: Biosilk 3D scaffolds for differentiation and proliferation of hPSCs

    Protocol for human pluripotent stem cell expansion, differentiation and organoid formation in 3D