Laminin protein information

Laminin nomenclature

Biolaminin product	Name of the protein	Old synonyms	Chain composition	Gene names of the chains
LN111	laminin-111	laminin-1, EHS laminin	α1β1γ1	LAMA1, LAMB1, LAMC1
LN121	laminin-121	laminin-3, S-laminin	α1β2γ1	LAMA1, LAMB2, LAMC1
LN211	laminin-211	laminin-2, merosin	α2β1γ1	LAMA2, LAMB1, LAMC1
LN221	laminin-221	laminin-4, S-merosin	α2β2γ1	LAMA2, LAMB2, LAMC1
LN332	laminin-332	laminin-5, kalinin, epiligrin, nicein, ladsin	α3β3γ2	LAMA3, LAMB3, LAMC2
LN411	laminin-411	laminin-8	α4β1γ1	LAMA4, LAMB1, LAMC1
LN421	laminin-421	laminin-9	α4β2γ1	LAMA4, LAMB2, LAMC1
LN511	laminin-511	laminin-10	α5β1γ1	LAMA5, LAMB1, LAMC1
LN521, MX521, CT521	laminin-521	laminin-11	α5β2γ1	LAMA5, LAMB2, LAMC1

Laminin chain primer sequences

A list of primers for the analysis of tissue and cell-specific gene expression of laminin chains.

	GenBank accession no.	5′ primer	3′ primer	Amplicon size, bp	Annealing temp, °C
LAMA1	NM_005559	GTCAGCGACTCAGAGTGTTTG	AACTTGGGTGAAAGATCGTCAG	185	55
LAMA2	NM_000426	GAACCCGCAGTGTCGAATCT	GGGGAGTTAGCTGCCTTCA	204	55
LAMA3	NM_000227	TAGACTTTGGAAGCACCTACTCA	GTTTATCAAGGACACCACAACCT	185	55
LAMA4	NM_002290	GCAGTGGAAATTCAGATCCCA	TAACCGCAGGTCATCAGTCAG	275	55
LAMA5	NM_005560	GGTGTGTCTCTGCGTGACAA	CCCCGACGTAGAAGACGAA	253	55
LAMB1	NM_002291	AGGAACCCGAGTTCAGCTAC	CACGTCGAGGTCACCGAAA	103	55
LAMB2	NM_002292	GCCCTGGGAACTTCGACTG	GGAAGCACTTCTTTTCGTCCTG	227	55
LAMB3	NM_000228	TCCTCTTGTGTTTTGCCCTG	CTGCCTGGAGTCACACTTG	206	55
LAMC1	NM_002293	TCGTCAACGCCGCCTTCAA	GTGTCGGCCTGGTTGTTGTA	184	55
LAMC2	NM_005562	CCAGGAGGGAAGTCTGTGATT	GCAGTGAATCCCATCAGTGTT	128	55
LAMC3	NM_006059	CCAGGTGCATCACATCCTGAG	GACCCCATTTGGGCTCCATT	236	55

GenBank sequence identifiers and annotations

Check your primers using Primer BLAST

Antibodies for human laminin isoforms

Targeting the Biolaminin human recombinant laminin isoforms, a panel of 17 monoclonal mouse antibodies has been developed to selectively recognize each specific subunit of the laminins, without any cross-reactivity to other subunits. The Laminin panel is developed by Atlas Antibodies using the same stringent conditions as for all PrecisA Monoclonals, guaranteeing defined specificity, multiplexing opportunities, secured continuity, and stable supply.

Laminin protein and gene expression in tissues

Study the expression of the laminin genes in different tissues, cell types and pathological states in The Human Protein Atlas.

The Human Protein Atlas is a program that aims to map all the human proteins in cells, tissues and organs using antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology.

Laminin-beta2 immunohistochemistry (LAMB2 in The Human Protein Atlas)

Laminin protein structure

See protein chain structure predictions in AlphaFold – an AI system developed by DeepMind and EMBL-EBI.

Search PDBe-KB (Protein Data Bank Europe Knowledge Base) for structural and functional protein annotations.